Silica nanoparticles as a delivery system for nucleic acid-based reagents.

Silica nanoparticles as a delivery system for nucleic acid-based reagents.
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DOI:
10.1039/b904197d
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发表时间:
2009-01-01
影响因子:
--
通讯作者:
Tamanoi F
Tamanoi F
中科院分区:
其他
文献类型:
--
作者:
Hom C;Lu J;Tamanoi F

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The transport of nucleic acid-based reagents is predicated upon developing structurally stable delivery systems that can preferentially bind and protect DNA and RNA, and release their cargo upon reaching their designated sites. Recent advancements in tailoring the size, shape, and external surface functionalization of silica materials have led to increased biocompatibility and efficiency of delivery. In this Feature Article, we highlight recent research progress in the use of silica nanoparticles as a delivery vehicle for nucleic acid-based reagents.
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