Poverty and chronic illness: why safety net programs matter.
Poverty and chronic illness: why safety net programs matter.
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贫困和慢性病：安全网计划为何重要。
DOI：
10.1038/s41390-019-0363-2
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发表时间：
2019
影响因子：
3.6
通讯作者：
Chahroudi,Ann
中科院分区：
文献类型：
--
作者：
Bloch,Deborah;Chahroudi,Ann
由Kochmanski、Oliveira和MonthéDrèze以及他们各自的团队撰写的本月刊《儿科研究》中的文章强调了体重和营养对儿科健康的重要性，这里我们将在贫困的背景下讨论这一点，贫困是健康的一个太常见的社会决定因素。这三篇文章涉及儿童不健康体重的不同因素和后果。在试图揭示后天和自然在儿童肥胖症发展中的贡献时，Kochmanski等人。利用密歇根动量中心健康家庭项目的队列，强调表观遗传学的作用，在不同年龄段的儿童中，与年龄相关的DNA甲基化存在于七个遗传位点。1 Oliveira等人。提出在肥胖的拉丁裔男性中，代谢综合征比阻塞性睡眠呼吸暂停的严重程度更会导致自主神经功能障碍，2和Monthé-Drèze等人。探讨母体肥胖与子代神经发育不良的关系。3这些文章支持需要继续研究可改变的因素，以预防儿童肥胖和营养不良，并呼吁提供资源来解决其根源，如早期生活中的贫困。众所周知，在发展中国家和发达国家，不健康的体重都会导致短期和长期的不利健康后果。贫穷和不健康的体重是密不可分的。尽管肥胖症和营养不良似乎是两种结果，但它们往往是由相同的因素驱动的：难以获得或负担不起健康食品(称为粮食不安全)。生命早期的营养不良与慢性疾病有关，如糖尿病、高脂血症和成年后的心血管疾病，所有这些都与肥胖有关。4.
Articles in this month’s issue of Pediatric Research authored by Kochmanski, Oliveira, and Monthé-Drèze and their respective teams emphasize the importance of weight and nutrition on pediatric health, which here we will discuss in the context of poverty, a far too common social determinant of health. These three articles touch upon different contributors to and outcomes of unhealthy weight in children. In attempting to unravel the contribution of nurture vs. nature in childhood obesity development, Kochmanski, et al. utilizing a cohort from the Michigan Momentum Center Healthy Families Project, highlight the role of epigenetics by age-related DNA methylation at seven genetic sites in children of different age groups. 1 Oliveira, et al. propose that metabolic syndrome in obese Latino males, more so than severity of obstructive sleep apnea, causes autonomic dysfunction, 2 and Monthé-Drèze, et al. investigate the relationship between maternal obesity and poor neurodevelopmental outcomes of offspring. 3 These articles support the need for continued research on modifiable factors to prevent childhood obesity and malnutrition and call for resources to address their root causes, such as poverty, in early life.It is well established that in both developing and developed countries, unhealthy weight leads to both short term and long term adverse health outcomes. Poverty and unhealthy weight go hand-in-hand. Though they are seemingly dichotomous outcomes, both obesity and malnutrition are often driven by the same factors: poor access to or unaffordability of healthy foods (termed food insecurity). Malnutrition early in life has been linked to chronic illnesses, such as diabetes, hyperlipidemia, and cardiovascular disease in adulthood, which are all also associated with obesity. 4