A transmission electron microscopy study of mineralization in age-induced transparent dentin
A transmission electron microscopy study of mineralization in age-induced transparent dentin
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DOI：
10.1016/j.biomaterials.2005.05.059
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发表时间：
2005-12-01
期刊：
影响因子：
14
通讯作者：
Ritchie, RO
中科院分区：
文献类型：
--
作者：
Porter, AE;Nalla, RK;Ritchie, RO
众所周知，改变的牙齿更容易发生骨折，特别是在修复或牙髓修复之后；因此，了解改变形式的牙本质的结构是很重要的，牙本质是人类牙齿中最丰富的组织，以便更好地确定这种骨折的增加倾向。透明的(或硬化性的)牙本质就是这样一种改变形式，其中牙本质小管被矿物质堵塞，这是衰老的自然渐进结果。本研究利用高分辨电子显微镜研究老化对牙本质矿物相的影响。这些研究表明，透明牙本质中的管间矿物晶体较小，而管内矿物(沉积在小管内的较大晶体)的化学成分与周围的管间矿物相似。出射波重建的晶面图像表明，管内矿物具有纳米级的颗粒。这些观察结果支持透明牙本质形成的“溶解和再沉淀”机制。(C)2005爱思唯尔有限公司。保留所有权利。
It is known that fractures are more likely to occur in altered teeth, particularly following restoration or endodontic repair; consequently, it is important to understand the structure of altered forms of dentin, the most abundant tissue in the human tooth, in order to better define the increased propensity for such fractures. Transparent (or sclerotic) dentin, wherein the dentinal tubules become occluded with mineral as a natural progressive consequence of aging, is one such altered form. In the present study, high-resolution transmission electron microscopy is used to investigate the effect of aging on the mineral phase of dentin. Such studies revealed that the intertubular mineral crystallites were smaller in transparent dentin, and that the intratubular mineral (larger crystals deposited within the tubules) was chemically similar to the surrounding intertubular mineral. Exit-wave reconstructed lattice-plane images suggested that the intratubular mineral had nanometer-size grains. These observations support a "dissolution and reprecipitation" mechanism for the formation of transparent dentin. (c) 2005 Elsevier Ltd. All rights reserved.