Neurobehavioral Consequences of Early Exposure to Lead in Rhesus Monkeys: Effects on Cognitive Behaviors
Neurobehavioral Consequences of Early Exposure to Lead in Rhesus Monkeys: Effects on Cognitive Behaviors
复制标题
恒河猴早期接触铅的神经行为后果：对认知行为的影响
DOI：
10.1007/978-1-4615-9346-1_22
复制
发表时间：
1983
影响因子：
2.7
通讯作者：
P. Bushnell
中科院分区：
文献类型：
--
作者：
N. Laughlin;R. Bowman;E. Levin;P. Bushnell
The present paper reports on a series of studies of rhesus monkeys exposed to low levels of lead administered daily throughout the first year of life. These lead-treated monkeys have provided an animal model directed at understanding childhood lead toxicity. The results to be described here focus on a cognitive test paradigm, reversal learning (RL), in which a reliable, lead-associated performance deficit was elicited and studied in several successive experiments. The emphasis of this report is on investigations of the RL test procedure designed to discover task parameters which elicited, enhanced, or sustained the lead-associated RL deficit, and which might identify the nature of the cognitive dysfunction responsible for the deficit.
