Clinical Significance of B-Scan Averaging With SD-OCT
Clinical Significance of B-Scan Averaging With SD-OCT
复制标题
DOI：
10.3928/15428877-20110908-02
复制
发表时间：
2012-01-01
影响因子：
--
通讯作者：
Sadda, Srinivas R.
中科院分区：
文献类型：
--
作者：
Pappuru, Rajeev R.;Briceno, Cesar;Sadda, Srinivas R.
平均多次扫描是光学相干断层扫描的潜在优势。作者评估了 B 扫描平均对视网膜外部结构可视化的定性优势。对转至成像单元的 35 名患者的 1 只眼睛的 Cirrus OCT（Carl Zeiss Meditec，都柏林，加利福尼亚州）B 扫描进行了回顾性分析，这些患者接受了三种类型的扫描采集：无平均、4X 平均和 20X 平均。根据识别结构、亮度和连续性的能力，使用 0（最差）到 3 的定性等级进行质量屏蔽评估。质量得分在平均 4 倍时持续提高，但在 20 倍时仅略有提高。平均似乎对于评估外界膜和外核层具有统计学上显着的有益效果（P < .05），但对于视网膜色素上皮和内节/外节连接处的可视化没有显着益处。即使在平均相对较少的帧时，过采样或平均 B 扫描对于可视化外部视网膜子结构的好处也是显而易见的。这些发现可能有助于设计临床试验和临床实践中的采集方案。 [眼科手术激光成像 2012 年；43:63-68。]
Averaging multiple scans is a potential advantage of optical coherence tomography. The authors evaluate the qualitative benefits of B-scan averaging on the visualization of outer retinal structures. A retrospective analysis was performed on Cirrus OCT (Carl Zeiss Meditec, Dublin, CA) B-scans from 1 eye of 35 patients referred to the imaging unit who underwent three types of scan acquisitions: no averaging, 4X averaging, and 20X averaging. Masked assessment of quality was made using a qualitative scale of 0 (worst) to 3 according to the ability to identify structure, brightness, and continuity. Quality scores consistently improved with 4X averaging, but improved only slightly further with 20X. Averaging appeared to have a statistically significant beneficial effect for the assessment of the external limiting membrane and outer nuclear layer (P < .05), with no significant benefit for visualization of the retinal pigment epithelium and inner segment/outer segment junction. The benefits of oversampling or averaging B-scans for visualizing outer retinal substructures are apparent even when averaging relatively few frames. These findings may be helpful when designing acquisition protocols in clinical trials and clinical practice. [Ophthalmic Surg Lasers Imaging 2012;43:63-68.]