Bifurcated Aneurysm Location Predicts In-Stent Stenosis After Neuroform-EZ Stent-Assisted Coiling for Intracranial Aneurysm.
Bifurcated Aneurysm Location Predicts In-Stent Stenosis After Neuroform-EZ Stent-Assisted Coiling for Intracranial Aneurysm.
复制标题
分叉动脉瘤位置可预测 Neuroform-EZ 支架辅助弹簧圈栓塞治疗颅内动脉瘤后支架内狭窄
DOI：
10.3389/fneur.2022.873014
复制
发表时间：
2022
影响因子：
3.4
通讯作者：
Liu, Xinke
中科院分区：
文献类型：
--
作者：
You, Wei;Feng, Junqiang;Ge, Huijian;Jin, Hengwei;Liu, Peng;Li, Youxiang;Jiang, Yuhua;Liu, Xinke
关键词：
Neuroform EZ支架系统（Boston Scientific Corporation，Fremont，CA，United States）是第四代颅内动脉瘤支架，专为颅内血管系统设计，以支持动脉瘤治疗。在本研究中，我们分析了采用Neuroform EZ支架治疗的动脉瘤患者的连续系列，特别关注支架内狭窄（ISS）的发生率。对我中心的电子数据库进行了回顾性审查，以识别2016年1月至2018年10月期间使用Neuroform EZ支架进行动脉瘤治疗的所有颅内动脉瘤患者。在我院至少接受过一次数字减影血管造影（DSA）随访的患者入组本研究。支架内狭窄（ISS）分为轻度（<2-5%）、中度（2 - 5 -50%）或重度（>50%）。该研究包括114例患者（78例女性，68.4%;中位年龄57.2 ± 9岁），共116个动脉瘤。在116处病变中，20处（17.2%）在平均随访6.9 ± 1.7个月时被确定为ISS，30%（6/20）的ISS为轻度，50%（10/20）为中度，20%（4/20）为重度。没有患者出现症状或需要进一步干预。发生ISS的患者比未发生ISS的患者年轻（52.6 ± 7.8 vs. 57.9 ± 9; p = 0.016）。狭窄患者中位于动脉分叉处的动脉瘤比例显著高于位于侧壁动脉的动脉瘤比例（37.9 vs. 10.3%; p = 0.002）。在多变量分析中，患者年龄（OR = 0.94; 95% CI 0.88-0.998; p = 0.02）和分叉动脉瘤位置（OR = 4.59; 95% CI 1.54-13.67; p = 0.006）是ISS的独立预测因素。在这项回顾性研究中，Neuroform EZ支架置入后ISS的发生率为17.2%，所有ISS病例均无症状。年龄较小和分叉动脉瘤位置的患者更有可能发生ISS。虽然Neuroform EZ支架特别适用于分叉动脉瘤，但应重点关注该位置的ISS。
The Neuroform EZ stent system (Boston Scientific Corporation, Fremont, CA, United States) is a fourth-generation intracranial aneurysm stent designed specifically for the cerebrovasculature to support aneurysm treatment. In this study, we analyzed our consecutive series of patients with aneurysm treated with the Neuroform EZ stent, with special attention to the occurrence of in-stent stenosis (ISS). A retrospective review of our center's electronic database was conducted to identify all patients with intracranial aneurysms who underwent aneurysm treatment with the Neuroform EZ stent between January 2016 and October 2018. Patients with at least one digital subtraction angiography (DSA) follow-up in our hospital were enrolled in this study. In-stent stenosis (ISS) was graded as mild (<2–5%), moderate (25–50%), or severe (>50%). The study included 114 patients (78 women, 68.4%; median age 57.2 ± 9 years) with a total of 116 aneurysms. Of the 116 lesions, 20 were identified with ISS (17.2%) at a mean follow-up of 6.9 ± 1.7 months, and ISS was mild in 30% (6/20), moderate in 50% (10/20), and severe in 20% (4/20). No patients were symptomatic or required further intervention. Patients who developed ISS were younger than those without ISS (52.6 ± 7.8 vs. 57.9 ± 9; p = 0.016). The proportion of aneurysms located at the artery bifurcation was significantly higher in patients with stenosis than located at the sidewall artery (37.9 vs. 10.3%; p = 0.002). In the multivariable analysis, the patients' age (OR = 0.94; 95% CI 0.88–0.998; p = 0.02) and bifurcated aneurysm location (OR = 4.59; 95% CI 1.54–13.67; p = 0.006) were independent predictors of ISS. In this retrospective study, the incidence of ISS after Neuroform EZ stent placement was 17.2%, and all the ISS cases were asymptomatic. Patients with younger age and bifurcated aneurysm location are more likely to develop ISS. Although Neuroform EZ stent is particularly suitable for bifurcated aneurysms, the ISS for this location should be focused upon.
登录
查看更多内容
DOI：
10.1136/neurintsurg-2012-010583.rep
发表时间：
2014-01-01
影响因子：
4.8
作者：
Takemoto, Koichiro;Tateshima, Satoshi;Vinuela, Fernando
通讯作者：
Vinuela, Fernando
影响因子：
8.3
作者：
Lutsep, HL;Barnwell, S;King, P
通讯作者：
King, P
影响因子：
37.8
作者：
Kearney, M;Pieczek, A;Isner, JM
通讯作者：
Isner, JM
影响因子：
4.8
作者：
Lylyk, Pedro;Miranda, Carlos;Fiorella, David
通讯作者：
Fiorella, David
影响因子：
1.6
作者：
Yoon, Kyeong-Wook;Kim, Young-Joon
通讯作者：
Kim, Young-Joon