Enhancing Literacy in Cardiovascular Genetics: A Scientific Statement From the American Heart Association
Enhancing Literacy in Cardiovascular Genetics: A Scientific Statement From the American Heart Association
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DOI：
10.1161/hcg.0000000000000031
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发表时间：
2016-10-01
影响因子：
--
通讯作者：
Ware, Stephanie
中科院分区：
文献类型：
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作者：
Mital, Seema;Musunuru, Kiran;Ware, Stephanie
基因组学的进步正在增强我们对先天性和获得性心血管疾病以及中风的遗传基础的理解。这些进展包括发现导致或增加儿童和成人发病风险的基因，发现影响患者对药物反应的基因，以及开发遗传学指导的疾病治疗方法。然而，心血管和中风临床医生充分理解这些知识并将其应用于患者护理的能力却落后了。本声明阐述了心血管疾病和中风患者的护理专家应该了解遗传学;他们如何获得这些知识;他们如何跟上遗传学，基因组学和药物遗传学的进展;以及他们如何应用这些知识来改善心血管疾病和中风患者及其家属的护理。
Advances in genomics are enhancing our understanding of the genetic basis of cardiovascular diseases, both congenital and acquired, and stroke. These advances include finding genes that cause or increase the risk for childhood and adult-onset diseases, finding genes that influence how patients respond to medications, and the development of genetics-guided therapies for diseases. However, the ability of cardiovascular and stroke clinicians to fully understand and apply this knowledge to the care of their patients has lagged. This statement addresses what the specialist caring for patients with cardiovascular diseases and stroke should know about genetics; how they can gain this knowledge; how they can keep up-to-date with advances in genetics, genomics, and pharmacogenetics; and how they can apply this knowledge to improve the care of patients and families with cardiovascular diseases and stroke.