Visualizing ultrasonically induced shear wave propagation using phase-sensitive optical coherence tomography for dynamic elastography.
Visualizing ultrasonically induced shear wave propagation using phase-sensitive optical coherence tomography for dynamic elastography.
复制标题
使用相位敏感的光学相干断层扫描来可视化超声诱导的剪切波传播，以进行动态弹性摄影。
DOI：
10.1364/ol.39.000838
复制
发表时间：
2014-02-15
期刊：
影响因子：
3.6
通讯作者：
Wang RK
中科院分区：
文献类型：
--
作者：
Nguyen TM;Song S;Arnal B;Huang Z;O'Donnell M;Wang RK
我们报道了使用相敏光学相干断层扫描（PhS-OCT）来检测和跟踪由超声辐射力诱导的组织内的时间和空间剪切波传播。使用聚焦超声发射在样品中远程产生千赫兹范围的剪切波，并使用PhS-OCT跟踪其传播。局部剪切模量的横截面图是由模拟组织的局部剪切波速估计重建的。我们证明了将超声辐射力和PhS-OCT结合起来进行剪切模量高分辨率映射的可行性。
We report on the use of phase-sensitive optical coherence tomography (PhS-OCT) to detect and track temporally and spatially shear wave propagation within tissue induced by ultrasound radiation force. Kilohertz-range shear waves are remotely generated in sample using focused ultrasound emission and their propagation is tracked using PhS-OCT. Cross-sectional maps of the local shear modulus are reconstructed from local estimates of shear wave speed in tissue-mimicking phantoms. We demonstrate the feasibility of combining ultrasound radiation force and PhS-OCT to perform high-resolution mapping of the shear modulus.