The Standard for Control of Chronic Beryllium Disease

The Standard for Control of Chronic Beryllium Disease
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慢性铍病控制标准

DOI:
10.1080/1047322x.1998.10389543
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发表时间:
1998
期刊:
Applied Occupational and Environmental Hygiene
影响因子:
--
通讯作者:
M. Eisenbud
M. Eisenbud
中科院分区:
--
文献类型:
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作者:
M. Eisenbud

文献摘要

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美国原子能委员会制定2 μg/m3标准控制职业性慢性铍病(CBD)至今已近50年。这是当时提出的三个标准之一,也是为了控制社区空气污染的急性疾病和CBD。虽然旨在仅限于其承包商,但CBD的控制标准很快就被几个监管机构采用,并保持不变。几十年来,许多人认为该标准正在实现其目的,一些专家甚至认为该标准具有不必要的限制性。然而,随着20世纪80年代开始采用新的诊断技术,发现了以前会被遗漏的病例,导致病例重新出现,并对现有标准的有效性产生了怀疑。第一个这样的疑问是在20世纪70年代在日本提出的,但在公布的信息中存在重大差距,使得对数据的评估变得困难。
Abstract It is now almost 50 years since 2 μg/m3 was established by the U.S. Atomic Energy Commission for control of occupational chronic beryllium disease (CBD). This was one of three standards proposed at the time to also control the acute disease and CBD from pollution of community air. Although intended to be limited to its contractors, the standard for control of CBD was soon adopted by several regulatory agencies and has remained unchanged. For several decades it was believed by many that the standard was achieving its purpose, and some specialists even suggested that the standard was unnecessarily restrictive. However, with the introduction of new diagnostic techniques beginning in the 1980s, cases have been identified that would have formerly been missed, resulting in a resurgence of cases and casting doubt on the efficacy of the existing standard. The first such doubts were raised in Japan in the 1970s, but there were major gaps in the published information that made evaluation of the data diffic...