RELATIVE BIOLOGICAL EFFECTIVENESS OF TRITIUM BETA-PARTICLES AND CO-60 GAMMA-RAYS MEASURED BY LETHALITY IN CF1 MICE
RELATIVE BIOLOGICAL EFFECTIVENESS OF TRITIUM BETA-PARTICLES AND CO-60 GAMMA-RAYS MEASURED BY LETHALITY IN CF1 MICE
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DOI：
10.2307/3570515
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发表时间：
1957-01-01
影响因子：
3.4
通讯作者：
FURCHNER, JE
中科院分区：
文献类型：
--
作者：
FURCHNER, JE
本文比较了氚单次照射（HTO）与钴~（60）γ射线照射对小鼠的影响。伽马辐射的传输速率与消除氚水所产生的呈指数下降的氚剂量率相当，其强度通过移动的圆锥形铅屏蔽减弱。30天内，氚β粒子的致死率是Co ~（60）γ射线的1.7倍。以氚β辐射的相对生物效应为1.7，计算人体内氚的最大容许浓度，得出的数值为3.7 [mu]c，空气和水的最大容许浓度（连续照射）分别为5 x 10-6和0.1 [mu]c/cc。
The effect on mice of a single exposure to tritium (in-jected intraperitoneally as HTO) was compared with the effect of expo-sure to Co60 gamma-radiation. The gamma-radiation was delivered at a rate comparable to the exponentially decreasing dose rate of tritium resulting from the elimination of tritium water and its intensity was attenuated by means of a moving conical lead shield. Tritium beta- particles were 1.7 times as effective as Co60 gamma-radiation in pro-ducing mortality in 30 days. Calculation of the maximum permissible body concentration for tritium in man, with 1.7 taken for the relative biological effectiveness of tritium beta-radiation, gave a value of 3.7 [mu]c and maximum permissible concentrations (for continuous exposure) of 5 x 10-6 and 0.1 [mu]c/cc for air and water, respectively.