Developmental genetics and homology: a hierarchical approach

Developmental genetics and homology: a hierarchical approach
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DOI:
10.1016/s0169-5347(97)01125-7
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发表时间:
1997-10-01
影响因子:
16.8
通讯作者:
Abouheif, E
Abouheif, E
中科院分区:
生物学1区
文献类型:
--
作者:
Abouheif, E

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发育遗传学的新进展为连接发育和进化的研究提供了一座桥梁。然而,这些领域的成功整合依赖于对同源性概念的清晰理解,因此,发育遗传数据必须放在比较方法的背景下,以提供对性状进化和发育起源的洞察。对来自不同层次(基因、基因表达模式、胚胎起源和形态)的性状进行比较分析,可以潜在地揭示发育整合、机会和约束的情况。此外,这种方法对解决围绕同源性概念的现代争议具有重要意义。
New advances in developmental genetics are providing a bridge to connect the study of development and evolution. The successful integration of these fields, however, is dependent on having a clear understanding of the concept of homology, Therefore, developmental genetic data must be placed within the context of the comparative method to provide insight into the evolutionary and developmental origins of traits. The comparative analysis of traits derived from several hierarchical levels (genes, gene expression patterns, embryonic origins and morphology) can potentially reveal scenarios of developmental integration, opportunity and constraint, Moreover, this approach has implications for resolving modern controversies surrounding the concept of homology.