Electronic p-Chip-Based System for Identification of Glass Slides and Tissue Cassettes in Histopathology Laboratories.
Electronic p-Chip-Based System for Identification of Glass Slides and Tissue Cassettes in Histopathology Laboratories.
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DOI：
10.4103/jpi.jpi_64_17
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发表时间：
2018
影响因子：
--
通讯作者：
Riben M
中科院分区：
文献类型：
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作者：
Mandecki W;Qian J;Gedzberg K;Gruda M;Rodriguez EF;Nesbitt L;Riben M
标签系统是基于一个小型的，电子的，无线的，激光激活的微型转发器命名为“p-Chip”。p-Chip是一个硅集成电路，尺寸为600 μm × 600 μm × 100 μm。每个p-Chip都包含一个存储在其电子存储器中的唯一识别码，可以使用自定义读取器进行检索。这些特性使p-Chip可用作载玻片和组织盒上的不显眼且几乎不可察觉的ID标签。该系统由p-Chip标记的样品载体、可容纳两个物体的专用台式p-Chip ID读取器和附加读取器（Wand）组成，附加读取器带有适配器，用于读取垂直存放在抽屉中的载玻片的阅读ID。在载玻片上，p芯片用粘合剂附着在短边的中心，在试剂卡上-直接嵌入塑料中。通过将读取器带到芯片附近来执行ID读出。使用标准组织病理学实验室方案进行检测。观察到载玻片和试剂卡的ID阅读效率非常好。当处理过的幻灯片存储在垂直的文件抽屉中时，p-Chip保持可读，而无需将其从存储位置移除，从而提高了在集合中搜索的速度。在试剂卡上，通过一层薄薄的石蜡仍然可以读取ID。载玻片和组织盒都可以用同一个读取器读取，减少了对冗余设备的需求。p-Chip对组织病理学实验室中常用的所有化学挑战都是稳定的，可耐受极端温度，并在长期储存中保持耐用。该技术与实验室信息管理系统软件系统兼容。p-Chip系统非常适合组织病理学实验室中的载玻片和试剂卡识别。
The tagging system is based on a small, electronic, wireless, laser-light-activated microtransponder named “p-Chip.” The p-Chip is a silicon integrated circuit, the size of which is 600 μm × 600 μm × 100 μm. Each p-Chip contains a unique identification code stored within its electronic memory that can be retrieved with a custom reader. These features allow the p-Chip to be used as an unobtrusive and scarcely noticeable ID tag on glass slides and tissue cassettes. The system is comprised of p-Chip-tagged sample carriers, a dedicated benchtop p-Chip ID reader that can accommodate both objects, and an additional reader (the Wand), with an adapter for reading IDs of glass slides stored vertically in drawers. On slides, p-Chips are attached with adhesive to the center of the short edge, and on cassettes – embedded directly into the plastic. ID readout is performed by bringing the reader to the proximity of the chip. Standard histopathology laboratory protocols were used for testing. Very good ID reading efficiency was observed for both glass slides and cassettes. When processed slides are stored in vertical filing drawers, p-Chips remain readable without the need to remove them from the storage location, thereby improving the speed of searches in collections. On the cassettes, the ID continues to be readable through a thin layer of paraffin. Both slides and tissue cassettes can be read with the same reader, reducing the need for redundant equipment. The p-Chip is stable to all chemical challenges commonly used in the histopathology laboratory, tolerates temperature extremes, and remains durable in long-term storage. The technology is compatible with laboratory information management systems software systems. The p-Chip system is very well suited for identification of glass slides and cassettes in the histopathology laboratory.