THE RETINOBLASTOMA PROTEIN AND THE REGULATION OF CELL CYCLING
THE RETINOBLASTOMA PROTEIN AND THE REGULATION OF CELL CYCLING
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DOI:
10.1016/0968-0004(92)90443-d
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发表时间:
1992-08-01
影响因子:
13.8
通讯作者:
WEINBERG, RA
中科院分区:
文献类型:
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作者:
COBRINIK, D;DOWDY, SF;WEINBERG, RA
Increasing attention has been focused on how the retinoblastoma (RB) protein regulates cell growth. Recent evidence indicates that it is a substrate for phosphorylation by cyclin-dependent kinase-cyclin complexes and suggests that this phosphorylation modulates the ability of this protein to regulate transit through the cell cycle, perhaps in its G1 phase.