Human scalp evoked potentials related to the fusion between a sound source and its simulated reflection
Human scalp evoked potentials related to the fusion between a sound source and its simulated reflection
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人体头皮诱发电位与声源及其模拟反射之间的融合相关
DOI：
10.1371/journal.pone.0209173
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发表时间：
2019-01-09
期刊：
影响因子：
3.7
通讯作者：
Li, Liang
中科院分区：
文献类型：
--
作者：
Huang, Ying;Lu, Hao;Li, Liang
听觉系统需要融合来自声源的直达波(Lead)及其延时反射(Lag)，以实现单一的声音图像感知。这种超前-滞后融合在混响环境中的听觉处理中起着至关重要的作用。在这里，我们通过跟踪当两者之间的时间延迟为0、2或4ms时，由超前和滞后之间的相关性(BIC)中断所诱发的人类皮质电位来研究超前-滞后融合的神经相关性。BIC诱发了由N1和P2成分组成的头皮电位。这两个分量都受到延迟的调制。延迟对两个分量的幅度的影响是相似的，延迟的增加导致幅度的降低。相反，延迟不同地调制两个分量的潜伏期，延迟的增加导致P2潜伏期的增加，而不是N1潜伏期的增加。与P2潜伏期类似，主观检测BIC的反应时也随着延迟的延长而增加。这些发现表明，BIC诱发的N1和P2都是超前-滞后融合的神经关联者，相对于N1，P2可能更密切地与听者对融合的感知有关。因此，我们的研究为研究来自声源的直接声波与其反射之间的融合提供了一种神经生理学和客观的方法。
The auditory system needs to fuse the direct wave (lead) from a sound source and its time-delayed reflections (lag) to achieve a single sound image perception. This lead-lag fusion plays crucial roles in auditory processing in reverberant environments. Here, we investigated neural correlates of the lead-lag fusion by tracking human cortical potentials evoked by a break in the correlation (BIC) between the lead and lag when the time delay between the two was 0, 2, or 4 ms. The BIC evoked a scalp potential consisting of an N1 and a P2 component. Both components were modulated by the delay. The effects of the delay on the amplitude of the two components were similar, an increase of the delay resulting in a decrease of the amplitude. In contrast, the delay differently modulated the latency of the two components, an increase of the delay resulting in an increase of the P2 latency but not an increase of the N1 latency. Similar to the P2 latency, the reaction time for subjective detection of the BIC also increased with the delay. These findings suggest that both the N1 and the P2 evoked by the BIC are neural correlates of the lead-lag fusion and that, relative to the N1, the P2 may be more closely related to listeners’ perception of the fusion. Our study thus provides a neurophysiological and objective approach for investigating the fusion between the direct sound wave from a sound source and its reflections.