Assessment of Murine Retinal Function by Electroretinography

Assessment of Murine Retinal Function by Electroretinography
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DOI:
10.21769/bioprotoc.2218
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发表时间:
2017-04-05
期刊:
影响因子:
0.8
通讯作者:
Vollrath, Douglas
Vollrath, Douglas
中科院分区:
其他
文献类型:
--
作者:
Benchorin, Gillie;Calton, Melissa A.;Vollrath, Douglas

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视网膜电图(ERG)是检测视网膜功能的一种敏感、无创的方法。在本方案中,我们描述了一种在小鼠中进行ERG的方法。小鼠角膜上的隐形眼镜测量光感受器和下游视网膜细胞对光刺激的电响应,并分析收集的数据以评估视网膜功能。
The electroretinogram (ERG) is a sensitive and noninvasive method for testing retinal function. In this protocol, we describe a method for performing ERGs in mice. Contact lenses on the mouse cornea measure the electrical response to a light stimulus of photoreceptors and downstream retinal cells, and the collected data are analyzed to evaluate retinal function.