Imaging Fully Hydrated Whole Cells by Coherent X-Ray Diffraction Microscopy

Imaging Fully Hydrated Whole Cells by Coherent X-Ray Diffraction Microscopy
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DOI:
10.1103/physrevlett.110.098103
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发表时间:
2013-02-28
影响因子:
8.6
通讯作者:
Song, Changyong
Song, Changyong
中科院分区:
物理与天体物理1区
文献类型:
--
作者:
Nam, Daewoong;Park, Jaehyun;Song, Changyong

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Nanoscale imaging of biological specimens in their native condition is of long-standing interest, in particular with direct, high resolution views of internal structures of intact specimens, though as yet progress has been limited. Here we introduce wet coherent x-ray diffraction microscopy capable of imaging fully hydrated and unstained biological specimens. Whole cell morphologies and internal structures better than 25 nm can be clearly visualized without contrast degradation. DOI: 10.1103/PhysRevLett.110.098103