Palladium-catalyzed cyanation reaction of aryl halides using K4[Fe(CN)6] as non-toxic source of cyanide under microwave irradiation
Palladium-catalyzed cyanation reaction of aryl halides using K4[Fe(CN)6] as non-toxic source of cyanide under microwave irradiation
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DOI：
10.1002/aoc.1639
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发表时间：
2010-06-01
影响因子：
3.9
通讯作者：
Pirisedigh, Azadeh
中科院分区：
文献类型：
--
作者：
Hajipour, Abdol R.;Karami, Kazem;Pirisedigh, Azadeh
本文报道了在微波辐射下，以[Pd{C_6 H_2（CH_2CH_2NH_2）-（OMe）（2），3，4}（μ-Br）]（2）为催化剂，以K-4[Fe（CN）（6）]为绿色氰源，由芳基溴、芳基碘和芳基氯合成芳基腈的有效方法。该配合物已被证明是该反应的活性和有效的催化剂。在DMF中在130 ° C下使用催化量的该合成的钯络合物导致在短的反应时间内以优异的产率生产氰基芳烃。版权所有（C）2010约翰威利父子有限公司
An efficient method for preparation of aryl nitriles - using [Pd{C6H2(CH2CH2 NH2)-(OMe)(2),3,4} (mu-Br)](2) complex as an efficient catalyst and K-4[Fe(CN)(6)] as a green cyanide source-from aryl bromides, aryl iodides and aryl chlorides under microwave irradiation has been reported. This complex has been demonstrated to be an active and efficient catalyst for this reaction. Using a catalytic amount of this synthesized palladium complex in DMF at 130 degrees C led to production of the cyanoarenes in excellent yields in short reaction times. Copyright (C) 2010 John Wiley & Sons, Ltd.