Risk Factors for Severe Hand-Foot-Mouth Disease in Children in Hainan, China, 2011-2012
Risk Factors for Severe Hand-Foot-Mouth Disease in Children in Hainan, China, 2011-2012
复制标题
DOI：
10.1177/1010539515579123
复制
发表时间：
2015-10-01
影响因子：
2.5
通讯作者：
Umezaki, Masahiro
中科院分区：
文献类型：
--
作者：
Chen, Shao-Ming;Du, Jian-Wei;Umezaki, Masahiro
在南亚，严重/致命手足口病病例的发生率有所增加。在中国，2011年海南省与手足口病相关的死亡率最高。本研究调查了海南地区严重手足口病的危险因素。对海南省2011年和2012年手足口病调查数据库进行分析，比较重度（n = 980）和非重度（n = 1679）手足口病的生物学和行为特征。在调整混杂因素后，使用逻辑回归模型研究每个解释变量与手足口病严重程度之间的关系。人类肠道病毒71型感染，体温峰值约39摄氏度，居住在城市以外地区，曾到乡村诊所就诊，出生体重过低，从未母乳喂养，由祖父母照顾，照顾者有
The incidence of severe/fatal cases of hand-foot-mouth disease (HFMD) has increased in South Asia. In China, Hainan Province had the highest incidence of mortality associated with HFMD in 2011. This study investigated the risk factors for severe HFMD in Hainan. The HFMD survey database for Hainan Province for 2011 and 2012 was analyzed, and the biological and behavioral characteristics of severe (n = 980) and nonsevere (n = 1679) HFMD were compared. The association between each explanatory variable and the severity of HFMD was investigated using a logistic regression model after adjusting for confounders. Human enterovirus 71 infection, a peak body temperature >39 degrees C, living outside urban areas, visiting a village clinic, low birth weight, never breastfed, cared for by grandparents, and caregiver with