TOXICITY OF GAMMA KNIFE RADIOSURGERY IN THE TREATMENT OF INTRACRANIAL TUMORS IN PATIENTS WITH COLLAGEN VASCULAR DISEASES OR MULTIPLE SCLEROSIS
TOXICITY OF GAMMA KNIFE RADIOSURGERY IN THE TREATMENT OF INTRACRANIAL TUMORS IN PATIENTS WITH COLLAGEN VASCULAR DISEASES OR MULTIPLE SCLEROSIS
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DOI：
10.1016/j.ijrobp.2011.02.056
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发表时间：
2011-11-15
影响因子：
7
通讯作者：
Chan, Michael D.
中科院分区：
文献类型：
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作者：
Lowell, Dot;Tatter, Stephen B.;Chan, Michael D.
目的：为了评估毒性与胶原血管疾病（CVD）或多发性硬化症（MS）治疗颅内radiosurgery.Methods和Materials：2004年1月至2009年4月，6例MS和14例CVD患者与伽玛刀放射外科（GKRS）治疗颅内肿瘤。治疗的病变包括7例患者的15个脑转移瘤，11个良性脑肿瘤，1个低级别胶质瘤和1个海绵状血管畸形。根据放射治疗肿瘤学小组急性/晚期放射发病率评分标准对毒性进行分级。“罕见毒性”是指科学文献中报告的发生率为
Purpose: To assess toxicity in patients with either a collagen vascular disease (CVD) or multiple sclerosis (MS) treated with intracranial radiosurgery.Methods and Materials: Between January 2004 and April 2009, 6 patients with MS and 14 patients with a CVD were treated with Gamma Knife radiosurgery (GKRS) for intracranial tumors. Treated lesions included 15 total brain metastases in 7 patients, 11 benign brain tumors, 1 low grade glioma, and 1 cavernous malformation. Toxicities were graded by the Radiation Therapy Oncology Group Acute/Late Radiation Morbidity Scoring Criteria. "Rare toxicities" were characterized as those reported in the scientific literature at an incidence of