Simple anatomical measurements do not correlate significantly to individual peripheral nerve stimulation thresholds as measured in MRI gradient coils
Simple anatomical measurements do not correlate significantly to individual peripheral nerve stimulation thresholds as measured in MRI gradient coils
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DOI：
10.1002/jmri.10300
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发表时间：
2003-06-01
影响因子：
4.4
通讯作者：
Ramachandran, M
中科院分区：
文献类型：
--
作者：
Chronik, BA;Ramachandran, M
目的：检查正常人类受试者在磁共振成像 (MRI) 梯度线圈中的周围神经刺激 (PNS) 阈值，并确定是否可以根据总体生理测量来预测观察到的阈值。材料和方法：使用全身梯度线圈测量 21 名健康正常受试者的 PNS 阈值。受试者暴露于梯形回波平面成像 (EPI) 梯度波形，并测量引起 PNS 所需的梯度强度总变化 (DeltaG) 作为梯度切换时间 (tau) 持续时间的函数。根据受试者的简单生理测量（包括体重、身高、周长和平均体脂百分比）计算 PNS 阈值测量的相关系数和相应的 P 值，以确定是否存在任何容易观察到的依赖性。结果：未观察到阈值参数和总体生理测量之间令人信服的相关性。结论：这些结果表明受试者解剖结构的简单生理测量不太可能用于以受试者特定方式指导 MRI 扫描仪的操作为了提高梯度系统性能，同时避免 PNS。
Purpose: To examine peripheral nerve stimulation (PNS) thresholds for normal human subjects in magnetic resonance imaging (MRI) gradient coils, and determine if observed thresholds could be predicted based on gross physiologic measurements.Materials and Methods: PNS thresholds for 21 healthy normal subjects were measured using a whole-body gradient coil. Subjects were exposed to a trapezoidal echo-planar imaging (EPI) gradient waveform and the total change in gradient strength (DeltaG) required to cause PNS as a function of the duration of the gradient switching time (tau) were measured. Correlation coefficients and corresponding P values were calculated for the PNS threshold measurements against simple physiologic measurements taken of the subjects, including weight, height, girth, and average body fat percentage, in order to determine if there were any easily observable dependencies.Results: No convincing correlations between threshold parameters and gross physiologic measurements were observed.Conclusion: These results suggest it is unlikely that a simple physiologic measurement of subject anatomy can be used to guide the operation of MRI scanners in a subject-specific manner in order to increase gradient system performance while avoiding PNS.