Palladium‐Catalyzed Alkynylation: Palladium‐Catalyzed Alkynylation with Alkynylmetals and Alkynyl Electrophiles
Palladium‐Catalyzed Alkynylation: Palladium‐Catalyzed Alkynylation with Alkynylmetals and Alkynyl Electrophiles
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钯催化的炔基化：钯催化的炔基金属和炔基亲电子试剂的炔基化
DOI：
10.1002/0471212466.ch23
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发表时间：
2003
期刊：
影响因子：
4.1
通讯作者：
Caiding Xu
中科院分区：
文献类型：
--
作者：
E. Negishi;Caiding Xu
在本章中，作者讨论了Pd催化的芳基、烯基、苄基、烷基和酰基亲电试剂与金属亲核试剂的反应，导致碳-金属键的形成。介绍了Sonogashira和相关的Heck型炔氢取代反应。概述了Pd催化的预形成的炔基金属与有机卤化物的交叉偶联反应和共轭取代反应的真实例子。本章还包括以下类别的化合物的特别讨论：杂芳族化合物;手性化合物及其不对称合成;共轭低聚物的生物意义;共轭低聚物和聚合物的材料化学利益和天然产物。
In this chapter the authors discuss the Pd‐catalyzed reactions of aryl, alkenyl, benzyl, alkyl, and acyl electrophiles with metal nucleophiles leading to carbon‐metal bond formation. The Sonogashira and related Heck‐type alkyne hydrogen substitution reactions are presented. Genuine examples of the Pd‐catalyzed cross‐coupling reactions of preformed alkynylmetals with organic halides and the conjugate substitution reactions are outlined. The chapter also includes special discussion of the following classes of compounds: heteroaromatics; chiral compounds and their asymmetric synthesis; conjugated oligomers of biological significance; conjugated oligomers and polymers of materials chemical interest and natural products.