Hybridization of herpes simplex virus DNA and human ribosomal DNA and RNA.
Hybridization of herpes simplex virus DNA and human ribosomal DNA and RNA.
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单纯疱疹病毒 DNA 与人类核糖体 DNA 和 RNA 的杂交。
DOI：
10.1016/0042-6822(85)90280-6
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发表时间：
1985
期刊：
影响因子：
3.7
通讯作者：
Hyman,RW
中科院分区：
文献类型：
--
作者：
Jones,TR;Parks,CL;Spector,DJ;Hyman,RW
单纯疱疹病毒DNA长序列区末端反向重复序列中的一小段DNA可与人28S核糖体DNA和RNA杂交，但不能与18S核糖体DNA和RNA杂交。杂交在严格条件下发生，并且不被鸟嘌呤加胞嘧啶含量高的核酸阻断。这些数据有力地表明，杂交代表了真实的碱基序列同源性。
A small DNA segment from the inverted repeats at the termini of the unique long sequence region of herpes simplex virus DNA was found to hybridize with human 28 S ribosomal DNA and RNA but not 18 S ribosomal DNA and RNA. The hybridization occurred under stringent conditions and was not blocked by nucleic acids high in guanine plus cytosine content. These data strongly suggest that the hybridization represented authentic base sequence homology.