Subjective and objective hypersomnia highly prevalent in adults with epilepsy
Subjective and objective hypersomnia highly prevalent in adults with epilepsy
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DOI：
10.1016/j.yebeh.2020.107023
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发表时间：
2020-05-01
影响因子：
2.6
通讯作者：
Foldvary-Schaefer, Nancy
中科院分区：
文献类型：
--
作者：
Grigg-Damberger, Madeleine;Andrews, Noah;Foldvary-Schaefer, Nancy
Introduction: Sleepiness is among the most common complaints of people with epilepsy, but objective documentation is lacking. We systematically investigated subjective and objective sleepiness in an observational cross-sectional cohort of adults with epilepsy (AWE).Methods: This is a prospective study of AWE consecutively recruited without foreknowledge of sleep/wake complaints. Polysomnography (PSG) with 18-channel electroencephalography (EEG) followed by multiple sleep latency testing (MSLT) was performed. Patients completed the Epworth Sleepiness Scale (ESS), a single-item question assessing excessive daytime sleepiness (EDS), and a 7-day sleep and seizure diary. Multivariable linear models were used to assess the association between MSLT mean sleep latency (MSL) and interests with adjustment of covariates of interest. Receiver operating characteristics (ROC) analysis was performed to evaluate the discrimination capability of ESS on MSL < 8 min and
