Long-term prognosis in patients with Takotsubo syndrome
Long-term prognosis in patients with Takotsubo syndrome
复制标题
Takotsubo 综合征患者的长期预后
DOI：
10.1002/ejhf.1417
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发表时间：
2019
影响因子：
18.2
通讯作者：
Akashi Yoshihiro J.
中科院分区：
文献类型：
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作者：
Tsuchida W.;Kobayashi Y.;Inoue K.;Yoshihara K.;Ooie T.;Akashi Yoshihiro J.
Citro及其同事最近发表了题为“左心室射血分数严重降低的takotsubo综合征患者的长期结局”的文章1。这是一篇评估左心室射血分数（LVEF）降低的takotsubo综合征（TS）患者的长期预后的迷人文章。入院时LVEF <35%不仅是TS患者急性期的预后指标，也是长期随访的预后指标。虽然认为各种研究已经提供了足够的TS临床数据，但本研究的数据在TS预后方面提供了直接相关的提示和提示。TS以前被认为是一种良性疾病，不需要任何特定的治疗;然而，由于一些并发症和危及生命的病例，现在TS的预后被认为比以前不乐观。El-Battrawy等人证明了TS患者的预后指标2，并得出结论，LVEF小于35%是TS患者短期和长期死亡率的独立预测因子。Citro等人报告了来自意大利多中心登记研究数据的326例TS患者的结果，其中包括约3倍于先前发表数据的数据。最近，由西班牙研究小组发起的RETAKO登记研究报告称，心源性休克与TS 3患者的短期和长期预后相关。入院时收缩压降低被认为是TS患者的预后指标4;因此，这些事实支持先前提出并在立场声明5中描述的风险分层。
Citro and colleagues newly issued the article entitled “Long-term outcome in patients with takotsubo syndrome presenting with severely reduced left ventricular ejection fraction” 1. This is a fascinating article to assess the long-term prognosis of takotsubo syndrome (TS) patients with reduced left ventricular ejection fraction (LVEF). LVEF less than 35% on admission was the prognostic indicator not only in the acute phase but also in the long-term follow-up period in TS patients. It is thought that various studies have already presented enough clinical data in TS, although, the data of this study are presenting directly associated hints and tips in TS prognosis. TS is previously thought to be a benign condition not requiring any specific treatments; however, nowadays the prognosis of TS is regarded not optimistic than before due to several complications and life-threatening cases. El-Battrawy et al. demonstrated a prognostic indicator in TS patients 2 and concluded that LVEF less than 35% was the independent predictor of short-and long-term mortality in TS patients. Citro et al. reported the results of 326 patients with TS from the Italian multicenter registry data that included approximately 3 times as much as the previous published data. Recently, the RETAKO registry promoted by a Spanish researcher group reported that cardiogenic shock was associated with short-and long-term prognosis in patients with TS 3. The decreased systolic blood pressure on admission is thought to be a prognostic indicator in TS patients 4; thus, these facts support the risk stratification which has been previously proposed and described in the position statement 5.