Why should breast tumour detection go three dimensional?
Why should breast tumour detection go three dimensional?
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DOI：
10.1088/0031-9155/48/14/312
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发表时间：
2003-07-21
影响因子：
3.5
通讯作者：
Ning, R
中科院分区：
文献类型：
--
作者：
Chen, ZK;Ning, R
Although x-ray mammography is widely developed for breast tumour detection, it suffers from spatial superposition in its two-dimensional (2D) representation of a three-dimensional (3D) breast structure. Accordingly, 3D breast imaging, such as cone-beam computed tomography (CT), arises at the historic moment. In this paper, we theoretically elucidate the spatial superposition effect associated with x-ray mammography on breast tumour detection. This explanation is based on the line integral of x-ray traversing a composite breast model. As a result, we can characterize the difficulty of detecting small tumours in terms of local intensity contrast in x-ray images. In comparison, we also introduce cone-beam CT breast imaging for 3D breast volume representation, which offers advantages for breast mass segmentation and measurement. The discussion is demonstrated with an experiment with a breast surgical specimen. In conclusion, we strongly believe that 3D volumetric representation allows for more accurate breast tumour detection.
