Functional diversity of chitin synthases of Aspergillus nidulans in hyphal growth, conidiophore development and septum formation
Functional diversity of chitin synthases of Aspergillus nidulans in hyphal growth, conidiophore development and septum formation
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DOI：
10.1080/13693780802213332
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发表时间：
2009-01-01
期刊：
影响因子：
2.9
通讯作者：
Horiuchi, Hiroyuki
中科院分区：
文献类型：
--
作者：
Horiuchi, Hiroyuki
真菌几丁质酶分为七类。基因组序列分析的最新进展表明，丝状子囊菌基因组中含有7个以上的几丁质酶编码基因。为了阐明这些基因在形态发生和菌丝生长中的功能差异，我们克隆了构巢曲霉中6个几丁质酶编码基因，并对其功能进行了分析。这些结果表明，几丁质酶在结构和功能上是不同的，并在A. nidulans。
Fungal chitin synthases are classified into seven classes. Recent advances in genome sequence analyses have revealed that there are more than seven chitin synthase-encoding genes in the genome of filamentous ascomycete fungi. To clarify the functional differences among these genes in the morphogenesis and hyphal tip growth, we have cloned six chitin synthase-encoding genes from Aspergillus nidulans and analyzed their functions. The results obtained suggest that chitin synthases are structurally and functionally divergent and play crucial roles in the growth and morphogenesis of A. nidulans.