Prevalence of enteric pathogens among community based asymptomatic individuals
Prevalence of enteric pathogens among community based asymptomatic individuals
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DOI：
10.1046/j.1440-1746.2000.02089.x
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发表时间：
2000-03-01
影响因子：
4.1
通讯作者：
Fairley, CK
中科院分区：
文献类型：
--
作者：
Hellard, ME;Sinclair, MI;Fairley, CK
背景和目标：本研究的目的是描述在墨尔本，Australia.Methods的社区研究中的无症状个体的病原微生物的患病率：研究人群是一个子集的2803个人参加水质研究，基于社区的随机试验。粪便标本（1091）收集了3个月内从无症状的个人。对样本进行了一系列细菌检测，包括沙门氏菌、志贺氏菌和弯曲杆菌属。用Rota-Adeno乳胶试剂盒检测轮状病毒和腺病毒，用改良铁-苏木素永久染色法检测原虫。结果：1091份粪便标本中共鉴定出28种已知病原体，总携带率为2.6%。18份标本（1.6%）中存在贾第虫属，4份（0.4%）中存在沙门氏菌，1份（0.1%）中存在弯曲杆菌，4份（0.4%）中存在隐孢子虫，1份（0.1%）中存在腺病毒。在65例标本中发现人芽囊原虫。无病原体者的中位年龄为12.5岁，而有病原体者为6.6岁（P = 0.02）。结论：除贾第虫外，社区中无症状个体很少发现病原体。儿童的病原体患病率高于成人。(C)2000 Blackwell Science Asia Pty Ltd.
Background and Aims: The objective of this study was to describe the prevalence of pathogenic microorganisms in asymptomatic individuals in a community study in Melbourne, Australia.Methods: The study population was a subset of 2803 individuals participating in the Water Quality Study; a community based randomized trial. Faecal specimens (1091) were collected over a 3-month period from asymptomatic individuals. Specimens were tested for a range of bacteria including Salmonella, Shigella and Campylobacter species. Rotavirus and adenovirus were detected using a Rota-Adeno latex kit, and protozoa were detected using a permanent stain (modified iron-haemotoxylin).Results: Twenty-eight known pathogens were identified from the 1091 faecal specimens, a total carriage rate of 2.6%. Giardia species were present in 18 specimens (1.6%), Salmonella in four (0.4%), Campylobacter in one (0.1%), Cryptosporidium in four (0.4%) and adenovirus in one (0.1%). Blastocystis hominis was found in 65 specimens. The median age of those without a pathogen was 12.5 years compared with 6.6 years for those with a pathogen (P = 0.02).Conclusions: Except for Giardia, pathogens were rarely found in asymptomatic individuals in the community. The prevalence of pathogens was higher in children than adults. (C) 2000 Blackwell Science Asia Pty Ltd.