A Human-Phantom Coupling Experiment and A Dispersive Simulation Model for Investigating the Variation of Dielectric Properties of Biological Tissues
A Human-Phantom Coupling Experiment and A Dispersive Simulation Model for Investigating the Variation of Dielectric Properties of Biological Tissues
复制标题
用于研究生物组织介电性能变化的人模耦合实验和色散仿真模型
DOI：
10.1016/j.compbiomed.2015.03.029
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发表时间：
2015
影响因子：
7.7
通讯作者：
W
中科院分区：
文献类型：
--
作者：
Gomez-Tames;J.; Fukuhara;Y.; He;S.; Saito;K.; Ito;Koichi.; Yu;W
由于衰老、皮肤水分、肌肉去神经支配以及血流随温度的变化，组织的介电特性可能会发生变化。几项研究使用突发调制交替刺激来通过降低组织阻抗来改善激活和舒适度，作为用更少的能量产生肌肉激活的可能机制。生物组织介电特性对神经激活影响的研究提出了一个基本问题，即难以系统地改变所研究对象的形态因素和介电特性。我们通过模拟和实验研究来解决这个问题。这项实验研究是一种新颖的方法，它将具有已知且可调节介电特性的脂肪组织等效体模与人类大腿相结合。通过这种方式，可以修改所研究组织的分散，以系统地观察其对肌肉激活的影响。我们观察到，为了在阻抗降低的条件下产生给定量的肌肉或神经激活，需要增加电流的幅度，同时需要降低电压的幅度。
Variation of the dielectric properties of tissues could happen due to aging, moisture of the skin, muscle denervation, and variation of blood flow by temperature. Several studies used burst-modulated alternating stimulation to improve activation and comfort by reducing tissue impedance as a possible mechanism to generate muscle activation with less energy. The study of the effect of dielectric properties of biological tissues in nerve activation presents a fundamental problem, which is the difficulty of systematically changing the morphological factors and dielectric properties of the subjects under study. We tackle this problem by using a simulation and an experimental study. The experimental study is a novel method that combines a fat tissue-equivalent phantom, with known and adjustable dielectric properties, with the human thigh. In this way, the dispersion of the tissue under study could be modified to observe its effects systematically in muscle activation. We observed that, to generate a given amount of muscle or nerve activation under conditions of decreased impedance, the magnitude of the current needs to be increased while the magnitude of the voltage needs to be decreased.