Sociodemographic factors and delays in the diagnosis of six cancers: analysis of data from the "National Survey of NHS Patients: Cancer".

Sociodemographic factors and delays in the diagnosis of six cancers: analysis of data from the "National Survey of NHS Patients: Cancer".
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DOI:
10.1038/sj.bjc.6602623
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发表时间:
2005-06-06
影响因子:
8.8
通讯作者:
--
中科院分区:
医学1区
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--
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本文旨在探讨这六种癌症(乳腺癌、结肠直肠癌、肺癌、卵巢癌、前列腺癌或非霍奇金淋巴瘤)的社会人口学因素与诊断延迟组成部分(总延迟、患者和初级保健、转诊、二级保健)之间的关系。对来自“NHS患者全国调查:癌症”的患者报告数据进行了二次分析(65192例患者)。数据分析采用单变量分析和广义线性模型。在总延迟方面,GLM的研究结果显示,结直肠癌的显著因素是婚姻状况和年龄,肺癌和卵巢癌的显著因素均不显著,前列腺癌的显著因素是社会阶层,非霍奇金淋巴瘤的显著因素是年龄,乳腺癌的显著因素是婚姻状况和种族。当发现任何组成延迟之间存在关联时,关联的方向总是相同的(女性受试者比男性受试者延迟更长,年轻人比老年人延迟更长,单身和分居/离婚的人比已婚的人延迟更长,社会阶层较低的群体比社会阶层较高的群体延迟更长,黑人和南亚人比白人延迟更长)。这些发现应该影响旨在减少诊断延迟的干预措施的设计,目的是通过早期诊断改善发病率、死亡率和心理结果。
This paper aims to explore the relationship between sociodemographic factors and the components of diagnostic delay (total, patient and primary care, referral, secondary care) for these six cancers (breast, colorectal, lung, ovarian, prostate, or non-Hodgkin's lymphoma). Secondary analysis of patient-reported data from the ‘National Survey of NHS patients: Cancer’ was undertaken (65 192 patients). Data were analysed using univariate analysis and Generalised Linear Modelling. With regard to total delay, the findings from the GLM showed that for colorectal cancer, the significant factors were marital status and age, for lung and ovarian cancer none of the factors were significant, for prostate cancer the only significant factor was social class, for non-Hodgkin's lymphoma the only significant factor was age, and for breast cancer the significant factors were marital status and ethnic group. Where associations between any of the component delays were found, the direction of the association was always in the same direction (female subjects had longer delays than male subjects, younger people had longer delays than older people, single and separated/divorced people had longer delays than married people, lower social class groups had longer delays than higher social class groups, and Black and south Asian people had longer delays than white people). These findings should influence the design of interventions aimed at reducing diagnostic delays with the aim of improving morbidity, mortality, and psychological outcomes through earlier stage diagnosis.
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发表时间: 2002-04-08
影响因子: 8.8
作者:
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通讯作者: Brenner, H
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发表时间: 2004-07-01
影响因子: 2.6
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发表时间: 1999-01-01
期刊: ANNALS OF SURGERY
影响因子: 9
作者:
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通讯作者: Bernstein, JL