Primary cutaneous peripheral T‐cell lymphoma, not otherwise specified, associated with lymphomatoid papulosis after a 9‐year follow up: A case report
Primary cutaneous peripheral T‐cell lymphoma, not otherwise specified, associated with lymphomatoid papulosis after a 9‐year follow up: A case report
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原发性皮肤外周 T 细胞淋巴瘤（未另有说明）9 年随访后与淋巴瘤样丘疹病相关：病例报告
DOI：
10.1111/1346-8138.15351
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Jinnin Masatoshi
中科院分区：
文献类型：
--
作者：
Muraoka Kyoko;Fujimoto Masakazu;Iwahashi Yoshifumi;Matsuzaki Ibu;Yonei Nozomi;Murata Shin‐ichi;Jinnin Masatoshi
淋巴瘤样丘疹病（LyP）是一种自限性皮肤T淋巴细胞增生性疾病，可发展为恶性淋巴瘤。大多数先前报道的相关淋巴瘤是原发性皮肤间变性大细胞淋巴瘤和蕈样真菌病，死亡率低。我们报告一例原发性皮肤外周T细胞淋巴瘤，无其他特异性（pcPTCL - NOS），经长期随访后与LyP相关。患者为一名79岁的日本男性，随访9年。他的前额突然出现了一个3厘米的溃疡，这被诊断为LyP的恶化。保守治疗后病变消退，但患者很快发展为多灶性pcPTCL - NOS。此后，患者出现肺炎和脑梗死，并在恶性淋巴瘤发病后几个月内死亡。LyP患者可发展为侵袭性皮肤淋巴瘤。本病例再次强调了对持续性LyP患者进行仔细随访的必要性。
Lymphomatoid papulosis (LyP) is a self‐limiting cutaneous T‐cell lymphoproliferative disorder that may progress into malignant lymphoma. Most of the previously reported associated lymphomas are primary cutaneous anaplastic large‐cell lymphoma and mycosis fungoides with a low mortality rate. We report a case of primary cutaneous peripheral T‐cell lymphoma, not otherwise specified (pcPTCL‐NOS), associated with LyP after long‐term follow up. The patient was a 79‐year old Japanese man followed up for 9 years. He suddenly developed a 3‐cm ulcerated lesion on his forehead, which was diagnosed as an exacerbation of LyP. The lesion regressed after conservative treatment, but the patient soon developed multifocal pcPTCL‐NOS. Thereafter, the patient developed pneumonia and cerebral infarction and died within a few months of the onset of malignant lymphoma. Aggressive cutaneous lymphoma may develop in LyP patients. The present case re‐emphasizes the need for careful follow up of patients with persistent LyP.
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一例原发性皮肤外周T细胞淋巴瘤，未另说明，具有细胞毒性表型，显示全身多发性溃疡
影响因子：
1.7
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K. Obara;Sumiyuki Mii;Y. Amoh
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DOI：
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DOI：
10.1097/pas.0000000000001256
发表时间：
2019
期刊：
The American Journal of Surgical Pathology
影响因子：
--
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A. Saggini;R. Fink‐Puches;C. Cota;V. Lora;H. Potzinger;C. Massone;L. Cerroni
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影响因子：
2
作者：
C. Magro;Luke C. Olson;S. Momtahen
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