Meta-analysis of factors related to health services that predict treatment default by tuberculosis patients
Meta-analysis of factors related to health services that predict treatment default by tuberculosis patients
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DOI：
10.1590/s0102-311x2008001600003
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发表时间：
2008-01-01
期刊：
影响因子：
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通讯作者：
Braga, José Ueleres
中科院分区：
文献类型：
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作者：
Brasil, Pedro Emmanuel Alvarenga Americano do;Braga, José Ueleres
确定预测结核病 (TB) 治疗违约的因素有助于控制这一问题。当前的研究采用系统评价来调查结核病治疗违约与先前研究的卫生服务相关因素之间的关联。在 MEDLINE 和 LILACS 数据库以及正在评估的全文参考书目中检索了摘要。如果通过比较两个或多个组来评估结核病治疗默认情况并提取数据，则研究被纳入。总共纳入了 41 项研究来合并数据。可以将五种暴露结合起来：“难以获得医疗服务”； “需要住院治疗”； “遵守培训或支持”； “延迟开始治疗”； “就医之前要等待很长时间”。 “难以获得卫生服务”、“依从性培训或支持”以及“需要住院治疗”与结核病治疗违约有关。所有暴露均表现出异质性，这仅在一项中得到了解释。仅在一次曝光中检测到发表偏倚。
The identification of factors that predict tuberculosis (TB) treatment default can help control this problem. The current study used a systematic review to investigate associations between TB treatment default and previously studied factors related to health services. Abstracts were searched in the MEDLINE and LILACS databases and in the bibliography of the full texts under evaluation. Studies were included if TB treatment default was evaluated by comparing two or more groups and data could be extracted. A total of 41 studies were included for combining data. It was possible to combine five exposures: "difficult access to health services"; "need for hospitalization"; "training or support for adherence"; "delay in initiating treatment"; "long wait before medical attendance". "Difficult access to health services", "training or support for adherence", and "need for hospitalization" were associated with TB treatment default. All exposures demonstrated heterogeneity, which was only explained in one. Publication bias was only detected for one exposure.