A positive dose-response effect of vitamin D supplementation on site-specific bone mineral augmentation in adolescent girls:: A double-blinded randomized placebo-controlled 1-year intervention
A positive dose-response effect of vitamin D supplementation on site-specific bone mineral augmentation in adolescent girls:: A double-blinded randomized placebo-controlled 1-year intervention
复制标题
DOI：
10.1359/jbmr.060302
复制
发表时间：
2006-06-01
影响因子：
6.2
通讯作者：
Lamberg-Allardt, Christel
中科院分区：
文献类型：
--
作者：
Viljakainen, Heli T.;Natri, Anna-Mari;Lamberg-Allardt, Christel
在一项随机安慰剂对照的研究中，对212名钙摄入充足的青春期女孩补充维生素D对骨矿物质增加的影响进行了研究。DXA测定的骨矿物质增加增加与补充在股骨和腰椎中的剂量反应方式。补充减少尿排泄的再吸收标志物，但没有影响的形成标志物。
The effect of vitamin D supplementation on bone mineral augmentation in 212 adolescent girls with adequate calcium intake was studied in a randomized placebo-controlled setting. Bone mineral augmentation determined by DXA increased with supplementation both in the femur and the lumbar vertebrae in a dose-responsive manner. Supplementation decreased the urinary excretion of resorption markers, but had no impact on formation markers.