Time-compressed preplay of anticipated events in human primary visual cortex.
Time-compressed preplay of anticipated events in human primary visual cortex.
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DOI：
10.1038/ncomms15276
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发表时间：
2017-05-23
影响因子：
16.6
通讯作者：
de Lange FP
中科院分区：
文献类型：
--
作者：
Ekman M;Kok P;de Lange FP
感知是由对未来事件的预期引导的。据推测，这个过程可以通过早期视觉皮层的模式完成来实现，其中仅在提供视觉输入的子集后重新创建刺激序列。在这里，我们使用超快功能磁共振成像来测试这一假设，以测量人类志愿者视觉皮层 (V1) 中精确定义的感受野位置的 BOLD 活动。我们发现，在让受试者熟悉空间序列后，仅闪烁序列的起点会触发 V1 中的活动波，类似于完整的刺激序列。与实际刺激序列相比，这种预玩活动在时间上被压缩，并且即使当注意力从刺激序列转移时仍然存在。因此，预播放可能构成 V1 中时间序列的自动预测机制。感知是通过预测未来事件来引导的，但尚不清楚这是如何通过神经计算的。在这里，作者使用超快功能磁共振成像来表明人类在初级视觉皮层中预演预期的视觉序列，并且这种预演与更快地检测刺激相关。
Perception is guided by the anticipation of future events. It has been hypothesized that this process may be implemented by pattern completion in early visual cortex, in which a stimulus sequence is recreated after only a subset of the visual input is provided. Here we test this hypothesis using ultra-fast functional magnetic resonance imaging to measure BOLD activity at precisely defined receptive field locations in visual cortex (V1) of human volunteers. We find that after familiarizing subjects with a spatial sequence, flashing only the starting point of the sequence triggers an activity wave in V1 that resembles the full stimulus sequence. This preplay activity is temporally compressed compared to the actual stimulus sequence and remains present even when attention is diverted from the stimulus sequence. Preplay might therefore constitute an automatic prediction mechanism for temporal sequences in V1. Perception is guided by anticipating future events, but it is not clear how this is computed neurally. Here, the authors use ultra-fast fMRI to show that humans preplay anticipated visual sequences in the primary visual cortex and that this preplay correlates with faster detection of the stimuli.