Hierarchy of pulp capping and repair activities responsible for dentin bridge formation.
Hierarchy of pulp capping and repair activities responsible for dentin bridge formation.
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发表时间：
2002-08
影响因子：
1.4
通讯作者：
P. Murray;Abeer A Hafez;Anthony J. Smith;C. Cox
中科院分区：
文献类型：
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作者：
P. Murray;Abeer A Hafez;Anthony J. Smith;C. Cox
盖髓变量在牙髓暴露后介导牙髓修复活动和牙本质桥形成的重要性尚未得到很好的理解。因此，本研究的目的是调查盖髓变量对三级牙本质桥形成的影响。材料与方法根据ISO使用指南，使用氢氧化钙[Ca（OH）2]、树脂改性玻璃离子（RMGI）和树脂基复合材料（RBC）修复161颗非人灵长类动物牙齿的牙髓暴露。收集7 ~ 720天的牙齿，观察导致牙本质桥形成的牙髓修复活动。使用McKays染色法检测细菌。使用ISO标准对牙髓活性进行组织形态计量学分类，并使用ANOVA统计进行统计学分析。结果盖髓后牙本质桥面积与盖髓时间、盖髓材料、细菌微渗漏、牙本质桥中手术碎屑面积的关系由大到小依次为：盖髓时间（P = 0.0009）、盖髓材料（P = 0.0252）、细菌微渗漏（P = 0.0358）、牙本质桥中手术碎屑面积（P = 0.0362）。另外10个盖髓变量被认为是不太重要的。观察盖髓材料、手术碎屑、隧道缺损、细菌微渗漏、炎症反应与牙本质桥形成的关系。细菌污染率分别为18.6%、22.2%和47.0%。
PURPOSE The importance of pulp capping variables which mediate pulp repair activities and dentin bridge formation following pulp exposure are not well understood. Consequently, the aim of this study was to investigate the effects of pulp capping variables on tertiary dentin bridge formation. MATERIALS AND METHODS Calcium hydroxide [Ca(OH)2], resin-modified glass-ionomer (RMGI) and resin-based composite (RBC) were used to restore pulp exposures prepared in 161 nonhuman primate teeth, according to ISO usage guidelines. Teeth were collected from between 7 and 720 days to observe the pulp repair activities leading to dentin bridge formation. Bacteria were detected using McKays stain. Pulp activity was categorized histomorphometrically using ISO standards, and analyzed statistically using ANOVA statistics. RESULTS The pulp capping variables in order of their relationship to dentin bridge area, from the most important to the least important were: time elapsed since pulp capping (P = 0.0009), pulp capping materials (P = 0.0252), bacterial microleakage (P = 0.0358) and area of operative debris in the dentin bridge (0.0362). A further 10 pulp capping variables were found to be less important. Relationships between pulp capping materials, operative debris, tunnel defects, bacterial microleakage, inflammation and dentin bridge formation were observed. Bacteria contaminated 18.6% of RBC, 22.2% of RMGI and 47.0% of Ca(OH)2 capped pulps.