The Arabidopsis thaliana RNA editing factor SLO2, which affects the mitochondrial electron transport chain, participates in multiple stress and hormone responses.
The Arabidopsis thaliana RNA editing factor SLO2, which affects the mitochondrial electron transport chain, participates in multiple stress and hormone responses.
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DOI：
10.1093/mp/sst102
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发表时间：
2014-02
期刊：
影响因子：
27.5
通讯作者：
Qiang Zhu;Jasper Dugardeyn;Chunyi Zhang;P. Mühlenbock;P. Eastmond;R. Valcke;B. De Coninck;Sevgi Oden;Michael Karampelias;B. Cammue;E. Prinsen;D. Van Der Straeten
中科院分区：
文献类型：
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作者：
Qiang Zhu;Jasper Dugardeyn;Chunyi Zhang;P. Mühlenbock;P. Eastmond;R. Valcke;B. De Coninck;Sevgi Oden;Michael Karampelias;B. Cammue;E. Prinsen;D. Van Der Straeten
最近，我们报道了新型线粒体 RNA 编辑因子 SLO2 对于线粒体电子传输至关重要，并且通过调节碳和能量代谢对植物生长至关重要。在这里，我们发现 SLO2 突变会导致对 ABA 过敏和对乙烯不敏感，这表明与应激反应有关。事实上，slo2 突变体在发芽阶段对盐和渗透胁迫高度敏感，而成年植物表现出增强的干旱和盐耐受性。此外，slo2突变体更容易受到灰葡萄孢感染。在 slo2 突变体中观察到核编码的应激反应基因以及线粒体编码的复合物 I 的 NAD 基因和替代呼吸途径基因的表达增加，并通过 ABA 处理进一步增强。此外，slo2 突变体中还记录了 H2O2 积累和氨基酸水平的改变。我们得出的结论是，植物对 ABA、乙烯、生物和非生物胁迫的敏感性需要 SLO2。尽管最近报道了两种与压力相关的 RNA 编辑因子，但这项研究证明了 SLO2 的独特作用，并进一步支持线粒体 RNA 编辑事件和压力反应之间的联系。
Recently, we reported that the novel mitochondrial RNA editing factor SLO2 is essential for mitochondrial electron transport, and vital for plant growth through regulation of carbon and energy metabolism. Here, we show that mutation in SLO2 causes hypersensitivity to ABA and insensitivity to ethylene, suggesting a link with stress responses. Indeed, slo2 mutants are hypersensitive to salt and osmotic stress during the germination stage, while adult plants show increased drought and salt tolerance. Moreover, slo2 mutants are more susceptible to Botrytis cinerea infection. An increased expression of nuclear-encoded stress-responsive genes, as well as mitochondrial-encoded NAD genes of complex I and genes of the alternative respiratory pathway, was observed in slo2 mutants, further enhanced by ABA treatment. In addition, H2O2 accumulation and altered amino acid levels were recorded in slo2 mutants. We conclude that SLO2 is required for plant sensitivity to ABA, ethylene, biotic, and abiotic stress. Although two stress-related RNA editing factors were reported very recently, this study demonstrates a unique role of SLO2, and further supports a link between mitochondrial RNA editing events and stress response.