Changes in the Association of Drug Use with Depressive Disorders in Recent Decades: The Case of Cocaine

Changes in the Association of Drug Use with Depressive Disorders in Recent Decades: The Case of Cocaine
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DOI:
10.3109/10826081003777550
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发表时间:
2010-08-01
影响因子:
2
通讯作者:
Miech, Richard A.
Miech, Richard A.
中科院分区:
医学4区
文献类型:
--
作者:
Bohnert, Amy S. B.;Miech, Richard A.

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可卡因的社会意义在20世纪80年代和90年代发生了变化。本研究调查了可卡因使用者心理状况的变化。我们使用了1981年(n = 3,006; 60%女性)和1993-1994年(n = 1,679; 52%女性)期间由国家精神健康研究所资助的流行病学集水区研究的巴尔的摩数据。诊断访谈计划测量可卡因使用和抑郁症(心境恶劣,重度抑郁症)。1981年和1993-1994年可卡因使用与抑郁症的比值比分别为1.28和3.53。结果表明,可卡因使用和抑郁症之间存在历史时期效应。限制和影响进行了讨论。
The social meaning of cocaine changed during the 1980s and 1990s. The present study examined changes in the psychological profile of cocaine users. We used Baltimore data of the National Institute of Mental Health-funded Epidemiologic Catchment Area study during 1981 (n = 3,006; 60% female) and 1993-1994 (n = 1,679; 52% female). The diagnostic interview schedule measured cocaine use and depressive disorders (dysthymia, major depressive disorder). The odds ratio of cocaine use for those with depression was 1.28 and 3.53 in 1981 and 1993-1994 respectively. The results suggest a historical period effect in the association of cocaine use and depression. Limitations and implications are discussed.