ULTRASOUND IMAGING IN THE DIAGNOSIS OF MUSCLE DISEASE
ULTRASOUND IMAGING IN THE DIAGNOSIS OF MUSCLE DISEASE
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DOI：
10.1016/s0022-3476(82)80286-2
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发表时间：
1982-01-01
影响因子：
5.1
通讯作者：
DUBOWITZ, V
中科院分区：
文献类型：
--
作者：
HECKMATT, JZ;LEEMAN, S;DUBOWITZ, V
对60例肌肉门诊就诊的新患者和60例对照儿童的股四头肌静态B超表现进行了比较研究。在对照组中，骨和筋膜的可视化良好，在无回声的肌肉组织背景下清晰可见。在神经肌肉疾病儿童中发现了一个惊人的变化。肌营养不良与肌肉物质反射的回声强度增加相关，相应的骨回声丢失。脊髓性肌萎缩和神经病也显示肌肉回声沿着肌肉萎缩和s.c.深度增加。组织.各种先天性肌病也表现出变化。非神经肌肉原因引起肌张力减退的婴儿扫描正常。扫描改变的严重程度与功能障碍无关，有些儿童功能良好，但扫描异常。扫描上的改变程度与活检上肌肉结构的破坏程度相关。超声成像已被证明是一个有用的，非侵入性的筛查工具，在调查儿童神经肌肉疾病。
A comparative study was done of the static B-scan ultrasound appearance of the quadriceps muscle of the thigh in 60 new patients attending a muscle clinic and in 60 control children. In the control subjects, there was good visualization of bone and fascia, which stood out clearly against the background of echo-free muscle tissue. A striking change was found in children with neuromuscular disease. Muscular dystrophies were associated with an increase in the intensity of echo reflected from the muscle substance, with a corresponding loss of bone echo. Spinal muscular atrophies and neuropathies also showed an increase in muscle echo along with atrophy of the muscle and increase in depth of s.c. tissue. Various congenital myopathies also showed changes. Infants with hypotonia from nonneuromuscular causes had normal scans. Severity of change on the scan did not relate to functional disability, and some children had good function yet strikingly abnormal scans. The degree of change on the scan correlated with the degree of disruption of muscle architecture on biopsy. Ultrasound imaging has proved to be a useful, noninvasive screening tool in the investigation of children with neuromuscular disease.