A bosentan pharmacokinetic study to investigate dosing regimens in paediatric patients with pulmonary arterial hypertension: FUTURE-3
A bosentan pharmacokinetic study to investigate dosing regimens in paediatric patients with pulmonary arterial hypertension: FUTURE-3
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DOI：
10.1111/bcp.13267
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发表时间：
2017-08-01
影响因子：
3.4
通讯作者：
Bonnet, Damien
中科院分区：
文献类型：
--
作者：
Berger, Rolf M. F.;Gehin, Martine;Bonnet, Damien
目的本研究的目的是探讨波生坦给药频率从2 mg kg（-1）每日两次（b.i.d.）至2 mg kg（-1），每日三次（t.i.d.）在患有肺动脉高压（PAH）的儿童中（从3个月到
AimThe aim of the present study was to investigate whether increasing the bosentan dosing frequency from 2mg kg(-1) twice daily (b.i.d.) to 2mg kg(-1) three times daily (t.i.d.) in children with pulmonary arterial hypertension (PAH) (from 3months to