LONG-TERM IN-VIVO STUDY OF PLASMASPRAYED COATINGS ON TITANIUM-ALLOYS OF TETRACALCIUM PHOSPHATE, HYDROXYAPATITE AND ALPHA-TRICALCIUM PHOSPHATE
LONG-TERM IN-VIVO STUDY OF PLASMASPRAYED COATINGS ON TITANIUM-ALLOYS OF TETRACALCIUM PHOSPHATE, HYDROXYAPATITE AND ALPHA-TRICALCIUM PHOSPHATE
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DOI：
10.1016/0142-9612(94)90264-x
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发表时间：
1994-01-01
期刊：
影响因子：
14
通讯作者：
DEGROOT, K
中科院分区：
文献类型：
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作者：
KLEIN, CPAT;PATKA, P;DEGROOT, K
为了研究磷酸钙涂层与骨组织的相互作用，将标准尺寸的涂层钛栓植入犬股骨。分别于植入后3、5、15和28个月进行力学推出试验和组织学观察，评价羟基磷灰石、α-磷酸三钙（α-TCP）和磷酸四钙等离子喷涂涂层的骨结合和骨形成情况。在此期间，所有涂层类型均发生降解。α-TCP在植入3个月后显示出最显著的降解。羟基磷灰石和磷酸四钙在植入约5个月后显示出明显的降解迹象。植入5个月后，所有涂层的骨结合均略有增加。一般而言，所有类型的种植体在长期植入后显示出相似的骨反应、一些骨接触和沿表面的几个重塑陷窝沿着。
In order to study the interaction of calcium phosphate coatings with bone tissue, coated titanium plugs of standard size were implanted in dog femora. The bone bonding and bone formation of hydroxyapatite, alpha-tricalcium phosphate (alpha-TCP) and tetracalcium phosphate plasma-sprayed coatings were evaluated by mechanical push-out tests and histological observations after 3, 5, 15 and 28 months of implantation. During this time all coating types degraded. alpha-TCP showed the most significant degradation after 3 months of implantation. Hydroxyapatite and tetracalcium phosphate showed significant signs of degradation after about 5 months of implantation. All coatings showed a small increase in bone bonding after 5 months of implantation. In general, all types of implants showed similar bone response, some bone contact and several remodelling lacunae along the surfaces after long-term implantation.