Accuracy of oral specimen testing for human immunodeficiency virus
Accuracy of oral specimen testing for human immunodeficiency virus
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DOI：
10.1016/s0002-9343(97)00033-8
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发表时间：
1997-01-01
影响因子：
5.9
通讯作者：
Emmons, Wesley
中科院分区：
文献类型：
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作者：
Emmons, Wesley
由于口腔样本采集和检测技术的进步，可以非常准确地检测口腔液中的人类免疫缺陷病毒（HIV）抗体。报告的灵敏度为97.2-100%，特异性为97.7-100%，与基于血清的检测方法相当，并使口腔液有资格在高风险和低风险人群中筛查和诊断HIV感染。此外，口服液作为HIV检测介质比血清具有几个优势，包括更高的安全性、易于收集和患者可接受性。
Antibodies to human immunodeficiency virus (HIV) can be detected in oral fluid with great accuracy, due to technical advances in both the collection of oral samples and assays. Reported sensitivities of 97.2-100% and specificities of 97.7-100% compare well with those of serum-based assays and qualify oral fluid for the screening and diagnosis of HIV infection in both high- and low-risk populations. In addition, oral fluid offers several advantages over serum as a testing medium for HIV, including greater safety, ease of collection, and patient acceptability.