Maps, routes, and the hippocampus: a neural network approach.
Maps, routes, and the hippocampus: a neural network approach.
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地图、路线和海马体：一种神经网络方法。
DOI：
10.1002/hipo.450030312
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发表时间：
1993
期刊：
影响因子：
3.5
通讯作者：
Blair,HT
中科院分区：
文献类型：
--
作者：
Schmajuk,NA;Thieme,AD;Blair,HT
这项研究描述了海马体参与迷宫导航的实时，生物学上合理的神经网络。该系统由(1)目标寻求机制、(2)认知地图系统和(3)路线系统组成。目标寻求机制表现出探索性行为，直到找到目标或对目标产生足够强的预测。认知地图是一种拓扑地图，它存储了地点和可到达地点之间的联系，以及地点和奖励之间的联系。路线系统建立了线索和奖励之间的联系。这两个系统相互竞争，以建立与奖励的联系，认知系统通常掩盖路线系统。与先前的模型一致，假设海马调节皮层区域的认知地图存储，并调解认知地图和路线系统之间的竞争。与先前的模型一致，假设海马调节皮层区域的认知地图存储，并调解认知地图和路线系统之间的竞争。海马损伤后，动物利用路线系统在迷宫中导航。计算机模拟表明，该网络有效地描述了正常动物以及海马和皮质损伤动物的潜在学习、绕道行为和位置学习。
This study describes hippocampal participation in maze navigation in terms of a real‐time, biologically plausible neural network. The system is composed of (1) a goal‐seeking mechanism, (2) a cognitive map system, and (3) a route system. The goal‐seeking mechanism displays exploratory behavior until either the goal is found or a sufficiently strong prediction of the goal is generated. The cognitive map is a topological map that stores associations between places and views of accessible places, and between places and reward. The route system establishes associations between cues and reward. Both systems compete with each other to establish associations with the reward, with the cognitive system generally overshadowing the route system. In agreement with previous models, it is assumed that the hippocampus modulates the storage of cognitive maps in cortical areas and mediates the competition between cognitive maps and route systems. In agreement with previous models, it is assumed that the hippocampus modulates the storage of cognitive maps in cortical areas and mediates the competition between cognitive maps and route systems. After hippocampal lesions, animals navigate through mazes making use of the route system. Computer simulations show that the network effectively describes latent learning, detour behavior, and place learning in normal and hippocampal‐and cortical‐lesioned animals.