Dynamic geometry of the left ventricle during ventricular pacing: correlation with cardiac pumping action.
Dynamic geometry of the left ventricle during ventricular pacing: correlation with cardiac pumping action.
复制标题
心室起搏期间左心室的动态几何形状：与心脏泵血作用的相关性。
DOI：
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发表时间：
1978
影响因子：
2.2
通讯作者：
T. Arai
中科院分区：
文献类型：
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作者：
Kozui Miyazawa;T. Honna;Takashi Haneda;Kunio Shirato;T. Nakajima;T. Arai
在5只麻醉开胸犬上，用电影心血管造影术分析了心脏起搏引起的左心室收缩模式。采用犬右前斜位进行左心室造影。电刺激右心耳(RA)和两个室壁部位(RVO：右室流出道和LVA：左室心尖部)，频率为150次/min。比较了室性起搏和RA起搏的收缩模式和心脏动力学，RA起搏代表了正常的心室收缩顺序和程度。RVO起搏导致前壁收缩停滞，后壁收缩正常，而LVA起搏使心尖部收缩扩张，后壁收缩增强。均匀起搏使左室舒张末期容量(LVEDV)、每搏输出量(SV)和射血分数(EF)降低，而左心室收缩末期容量(LVESV)相对恒定。心脏起搏后血压明显降低。RVO起搏与LVA起搏之间仅有微小差异。认为室性起搏时SV和EF的降低是由心室的非同步收缩引起的，而与心肌收缩能力下降无关。
In five anesthetized open chest dogs, contraction patterns of the left ventricle induced by ventricular pacing were analyzed using cineangiocardiography. Left ventriculography was performed with dogs in the right anterior oblique position. The right atrial appendage (RA) and two ventricular sites (RVO: outflow tract of the right ventricle and LVA: apex of the left ventricle) were stimulated electrically at a rate of 150 per min. Contraction patterns and cardiodynamics in response to ventricular pacing were compared with those to RA pacing, which represents a normal sequence and extent of ventricular contraction. RVO pacing resulted in asyneresis of anterior wall and normal contraction of posterior wall, while LVA pacing produced a systolic expansion of the apex associated with enhanced contraction of the posterior wall. Ventricular pacing uniformly caused decreases in left ventricular end-diastolic volume (LVEDV), stroke volume (SV) and ejection fraction (EF), with relatively constant left ventricular end-systolic volume (LVESV). Blood pressure was significantly decreased with ventricular pacing. There were only minor differences of these parameters between RVO and LVA pacing. It was considered that a diminution of SV and EF during ventricular pacing resulted from the asynchronous contraction of the ventricle which was not related to decreased myocardial contractility.