Role of tumour markers, cytogenetics
Role of tumour markers, cytogenetics
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DOI：
10.1023/a:1008386130283
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发表时间：
1999-01-01
影响因子：
50.5
通讯作者：
Lamerz, R
中科院分区：
文献类型：
--
作者：
Lamerz, R
综述了常规肿瘤标志物和分子肿瘤标志物(TM)在胆胰腺恶性肿瘤诊断和监测中的作用。对于胆胰腺恶性肿瘤，继CEA作为胃肠道疾病的传统和基础TM之后，最主要的标志物是作为单唾液酸神经节苷脂/糖脂和唾液酸衍生物的CA19-9(sialyl-Lewis(A)，人类Lewis(A)血型决定簇)。在低浓度的健康人血清中检测到它。
A review is presented on the role of conventional and molecular tumour markers (TM) in diagnosis and monitoring of patients with biliopancreatic malignancies.For biliopancreatic malignancy, following CEA as more historical and basic TM of gastrointestinal diseases, the mainstay marker is CA 19-9 as monosialo-ganglioside/glycolipid and sialyl derivative of lacto-N-fucopentaose II (sialyl-Lewis(a), hapten of human Lewis(a) bloodgroup determinant). It is detected in serum of healthy individuals at low concentration