Rotavirus Entry: a Deep Journey into the Cell with Several Exits
Rotavirus Entry: a Deep Journey into the Cell with Several Exits
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DOI：
10.1128/jvi.01787-14
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发表时间：
2015-01-01
影响因子：
5.4
通讯作者：
Lopez, Susana
中科院分区：
文献类型：
--
作者：
Arias, Carlos F.;Silva-Ayala, Daniela;Lopez, Susana
轮状病毒是全世界婴幼儿急性胃肠炎的主要病原体。这些无包膜病毒使用不同类型的内吞作用进入细胞，并且根据病毒株，在退出到胞质空间之前行进到不同的内体区室。在这篇文章中，我们回顾了病毒进入细胞的不同阶段所涉及的病毒和细胞因素，并与读者分享了我们进入细胞以了解病毒进入细胞的过程。
Rotaviruses are the leading etiological agents of acute gastroenteritis in infants and young children worldwide. These nonenveloped viruses enter cells using different types of endocytosis and, depending on the virus strain, travel to different endosomal compartments before exiting to the cytosolic space. In this Gem, we review the viral and cellular factors involved in the different stages of a productive virus cell entry and share with the readers the journey that we have taken into the cell to learn about virus entry.