Variation in Timing, Duration, Intensity, and Direction of Adolescent Growth in the Mandible, Maxilla, and Cranial Base: The Fels Longitudinal Study
Variation in Timing, Duration, Intensity, and Direction of Adolescent Growth in the Mandible, Maxilla, and Cranial Base: The Fels Longitudinal Study
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DOI：
10.1002/ar.22918
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发表时间：
2014-07-01
影响因子：
2
通讯作者：
Sherwood, Richard J.
中科院分区：
文献类型：
--
作者：
Nahhas, Ramzi W.;Valiathan, Manish;Sherwood, Richard J.
在儿童和青少年时期，颅面复合体的生长时间、持续时间和强度存在相当大的个体差异。本文的目的是描述的程度，这种性状之间的变化和个人之间的Fels纵向研究（FLS）。多项式多水平模型被用来估计发病年龄，峰值速度，和青春期生长停止，这些年龄之间的时间，这些年龄之间的增长量，和峰值速度。这是在组和个体水平上完成的，用于下颌骨、上颌骨和颅底的长度、下颌角和鞍角的标准头影测量。数据来自FLS中293名4-24岁未接受治疗的男孩和女孩。青春期生长突增的时间一般来说在下颌骨和上颌骨之间没有显著差异，与颅底长度相比，下颌骨和上颌骨的发病年龄较早，峰值速度的年龄较晚，停止生长的年龄较晚。与长度相比，角度一般有较晚的发病年龄，峰值速度和停止增长。颅面复合体中特征的个体发育轨迹的准确表征对于寻求优化治疗时机的临床医生和对检查异时性感兴趣的解剖学家都是至关重要的。(C)2014 Wiley Periodicals，Inc.
There is considerable individual variation in the timing, duration, and intensity of growth that occurs in the craniofacial complex during childhood and adolescence. The purpose of this article is to describe the extent of this variation between traits and between individuals within the Fels Longitudinal Study (FLS). Polynomial multilevel models were used to estimate the ages of onset, peak velocity, and cessation of adolescent growth, the time between these ages, the amount of growth between these ages, and peak velocity. This was done at both the group and individual levels for standard cephalometric measurements of the lengths of the mandible, maxilla, and cranial base, the gonial angle, and the saddle angle. Data are from 293 untreated boys and girls age 4-24 years in the FLS. The timing of the adolescent growth spurt was, in general, not significantly different between the mandible and the maxilla, with each having an earlier age of onset, later age of peak velocity, and later age of cessation of growth as compared to the cranial base length. Compared to lengths, angles had in general later ages of onset, peak velocity, and cessation of growth. Accurate characterization of the ontogenetic trajectories of the traits in the craniofacial complex is critical for both clinicians seeking to optimize treatment timing and anatomists interested in examining heterochrony. (C) 2014 Wiley Periodicals, Inc.