Normal planum temporale asymmetry in dyslexics with a magnocellular pathway deficit
Normal planum temporale asymmetry in dyslexics with a magnocellular pathway deficit
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DOI：
10.1097/00001756-199902250-00030
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发表时间：
1999-02-25
期刊：
影响因子：
1.7
通讯作者：
Demb, JB
中科院分区：
文献类型：
--
作者：
Best, M;Demb, JB
发育性阅读障碍与颞平面 (PT) 半球对称性异常和大细胞视觉通路缺陷有关。我们检查了这两种异常之间的关系。使用矢状磁共振图像和三种方法，我们测量了有记录的大细胞缺陷的阅读障碍受试者和对照组的 PT。诵读困难受试者并未偏离正常的左侧 PT 不对称性，但两组患者通过排除沟组织的方法，左偏性均有所降低。结果表明，患有大细胞缺陷的阅读障碍受试者并不总是有 PT 对称性异常。相反，PT 对称性可能与阅读障碍的不同亚型有关。此外，任何受试者组中的 PT 不对称性取决于测量方法。 (C) 1999 年利平科特·威廉姆斯和威尔金斯。
DEVELOPMENTAL dyslexia has been associated with both abnormal hemispheric symmetry of the planum temporale (PT) and a deficit in the magnocellular visual pathway. We examined the relationship between these two abnormalities. Using sagittal magnetic resonance images and three methods, we measured the PT in dyslexic subjects with a documented magnocellular deficit and controls. Dyslexic subjects did not deviate from normal leftward PT asymmetry, but both groups became less left-lateralized with methods that excluded sulcul tissue. Results suggest that dyslexic subjects with a magnocellular deficit do not always have abnormal symmetry of the PT. PT symmetry may instead be related to a different subtype of dyslexia. In addition, PT asymmetry in any subject group depends on the measurement method. (C) 1999 Lippincott Williams & Wilkins.