Coatomer (COPI)-coated vesicles: role in intracellular transport and protein sorting

Coatomer (COPI)-coated vesicles: role in intracellular transport and protein sorting
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DOI:
10.1016/s0955-0674(97)80023-3
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发表时间:
1997-08-01
影响因子:
7.5
通讯作者:
Letourneur, F
Letourneur, F
中科院分区:
生物学2区
文献类型:
--
作者:
Cosson, P;Letourneur, F

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Cotom包被的囊泡被认为在细胞内运输的许多不同步骤中发挥作用。Cotom可能在内质网到高尔基体和高尔基体的正向运输中发挥作用,也可能在逆行运输和内吞途径中发挥作用。用来研究辅助者作用的各种方法都有局限性,研究这些方法有助于我们更好地界定有待回答的问题。
Coatomer-coated vesicles have been proposed to play a role in many distinct steps of intracellular transport. Coatomer potentially plays a role in forward transport from the endoplasmic reticulum to the Golgi apparatus and through the Golgi apparatus, It may also function in retrograde transport and in the endocytic pathway. There are limitations to the various approaches used to study the role of coatomer, and looking at these helps us to better define the questions that remain to be answered.