Individual differences in social desirability are associated with white-matter microstructure of the external capsule
Individual differences in social desirability are associated with white-matter microstructure of the external capsule
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DOI：
10.3758/s13415-017-0548-2
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发表时间：
2017-12-01
影响因子：
2.9
通讯作者：
Heekeren, Hauke R.
中科院分区：
文献类型：
--
作者：
Andrejevic, Milan;Meshi, Dar;Heekeren, Hauke R.
人类倾向于以积极的态度展现自己以获得社会认可。这种行为特征被称为社会期望，对于各种类型的社会成功都很重要。令人惊讶的是，对社会期望的神经基础的研究受到限制，并且仅集中于多巴胺受体结合的个体间差异。这些研究表明，具有高社会期望特征的个体纹状体中的多巴胺受体结合减少。有趣的是，无论社会期望如何，高多巴胺信号传导与低白质完整性相关。基于这些发现，我们假设特质的社会期望与外囊的白质微观结构之间存在正相关，外囊将纤维从前额叶皮层运送到纹状体。为了检验这一假设，我们收集了扩散张量成像数据，并检查了外部胶囊的分数各向异性与参与者的社会期望之间的关系——我们的分析揭示了正相关关系。作为第二个探索性步骤，我们检查了社会期望与整个大脑的白质微观结构之间的关联。我们的全脑分析揭示了多个主要白质束内的关联，表明社会理想的行为依赖于分布式大脑区域之间的连接。
Humans tend to present themselves in a positive light to gain social approval. This behavioral trait, termed social desirability, is important for various types of social success. Surprisingly, investigation into the neural underpinnings of social desirability has been limited and focused only on interindividual differences in dopamine receptor binding. These studies revealed reduced dopamine receptor binding in the striatum of individuals who are high in trait social desirability. Interestingly, high dopamine signaling has been associated with low white-matter integrity, irrespective of social desirability. Based on these findings, we hypothesized that a positive association exists between trait social desirability and the white-matter microstructure of the external capsule, which carries fibers to the striatum from the prefrontal cortex. To test this hypothesis, we collected diffusion tensor imaging data and examined the relationship between fractional anisotropy of the external capsule and participants' social desirability-our analysis revealed a positive association. As a second exploratory step, we examined the association between social desirability and white-matter microstructure throughout the whole brain. Our whole-brain analysis revealed associations within multiple major white-matter tracts, demonstrating that socially desirable behavior relies on connectivity between distributed brain regions.