Real-life outcomes of maraviroc-based regimens in HIV-1-infected individuals.
Real-life outcomes of maraviroc-based regimens in HIV-1-infected individuals.
复制标题
DOI：
10.1177/1545109712462454
复制
发表时间：
2013-01-01
影响因子：
--
通讯作者：
Wilkins, Edmund
中科院分区：
文献类型：
--
作者：
Babiker, Zahir Osman Eltahir;Douthwaite, Sam Thomas;Wilkins, Edmund
目的：回顾了我们单位使用马拉韦洛克的有效性和安全性，并回顾了我们的经验如何反映临床试验中的数据。方法：我们利用药房配药系统识别任何使用马拉韦洛克的患者，并进行病例记录回顾。结果：我们确定了27例使用马拉韦洛克作为抗逆转录病毒治疗一部分的患者。其中81%是男性，81%是英国白人。有治疗经验者26例，初治者1例。在改用马拉韦洛克治疗时，17名患者检测到HIV病毒载量，10名患者检测到HIV RNA水平
PURPOSE: The use of maraviroc in our unit was reviewed with regard to efficacy and safety and also reviewed with regard to how our experience reflects the data presented in clinical trials.METHODS: We utilized the pharmacy dispensary system to identify any patient dispensed maraviroc and conducted a case note review.RESULTS: We identified 27 patients who have been prescribed maraviroc as part of their antiretroviral treatment. In all, 81% were men and 81% were white British. There were 26 treatment-experienced patients and 1 treatment-naive patient. At the time of switching to maraviroc, 17 patients had detectable HIV viral loads and 10 had HIV RNA levels