An exploration of symmetry in early autism spectrum disorders: Analysis of lying
An exploration of symmetry in early autism spectrum disorders: Analysis of lying
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DOI：
10.1016/j.braindev.2008.04.005
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发表时间：
2009-02-01
影响因子：
1.7
通讯作者：
Muratori, Filippo
中科院分区：
文献类型：
--
作者：
Esposito, Gianluca;Venuti, Paola;Muratori, Filippo
背景资料：自闭症谱系障碍（ASD）儿童的早期识别被认为是他们的医疗管理和治疗的一个重要方面。运动障碍被认为是可能先于社会或语言异常的最初迹象之一。目的：通过观察的方法，验证通过运动将ASD婴儿与典型发育或智力迟钝的婴儿区分开来的可能性。研究方法：Eshkol-Wachman运动分析系统分析了在躺卧时的静态对称性（SS）和动态对称性（DS），应用于ASD儿童（n = 18）、典型发育（18）或发育迟缓（12）的前5个月或生命的回顾性离子视频。结果：ASD和两个对照组之间的SS（p <0.001）和DS（p <0.01）存在显著差异。在ASD中，两组婴儿可以根据较高（HLS）或较低（LLS）对称性水平进行区分。早发性ASD更可能属于LLS组。结论：我们认为，运动功能可以定义特定的亚组的早期ASD，弧相关的不同途径的综合征。LLS可以作为潜在自闭症的早期指标，从生命的最初几个月开始。(C)2008 Elsevier B. V.保留所有权利。
Background: Early identification of children with autism spectrum disorders (ASD) is recognized as a critical aspect of their medical management and treatment. Movement disorders are considered one of the first signs which probably precede social Or linguistic abnormalities. Objectives: to verify, through observational methods, the possibility of distinguishing infants with ASD from infants with typical development or with mental retardation by movement. Methods: The Eshkol-Wachman movement analysis system, which analyses static symmetry (SS) and dynamic symmetry (DS) during lying, was applied to retrospective]ionic videos regarding the first 5 months or life of children with ASD (n = 18), typical development (it 18), or developmental delay (it 12). Results: Significant differences between ASD and the two control groups were found for both SS (p < .001) and DS (p < .01). Within ASD two groups of infants could be differentiated oil the basis of the higher (HLS) or the lower (LLS) levels of symmetry. Early onset ASD are more likely to belong to the LLS group. Conclusion: We suggest that motor functioning may define specific subgroups of early ASD which arc related to different pathways to the syndrome. LLS Could be used as in early indicator of potential autism since the first months of life. (C) 2008 Elsevier B.V. All rights reserved.